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Selective screening for abdominal aortic aneurysm

C W Cole1, G B Hill, W J Millar

  • 1Ottawa General Hospital, Ontario.

Chronic Diseases in Canada
|April 1, 1996
PubMed
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Selective screening for abdominal aortic aneurysm (AAA) can improve cost-effectiveness. Incorporating multiple risk factors like age and smoking significantly reduces the number of men needing screening for early detection.

Area of Science:

  • Vascular Surgery
  • Preventive Medicine
  • Health Economics

Background:

  • Abdominal aortic aneurysm (AAA) is a potential target for early detection.
  • The cost-effectiveness of AAA screening requires further demonstration.
  • Targeted screening strategies may enhance intervention efficiency.

Purpose of the Study:

  • To estimate the cost-effectiveness of selective screening for AAA.
  • To identify optimal risk stratification methods for AAA screening.
  • To evaluate the impact of incorporating multiple risk factors into screening protocols.

Main Methods:

  • Utilized data from a hospital-based case-control study (78 AAA cases, 99 male controls).
  • Developed a logistic regression model to derive an AAA risk function based on age, smoking, hypertension, heart disease history, BMI, and HDL.

Related Experiment Videos

  • Estimated potential screening benefit by multiplying AAA risk by life expectancy for controls.

    • Main Results:

    • Screening 52% of elderly men based on age alone would yield 80% of the potential benefit.
    • Including age and smoking reduced the required screening population to 35%.
    • Incorporating all identified risk factors reduced the screening target to 17% of the elderly male population.

    Conclusions:

    • Selective screening for AAA is a promising strategy to improve cost-effectiveness.
    • Risk stratification using multiple factors significantly narrows the screening population.
    • Prospective studies are necessary to validate these predictive findings for AAA screening.