Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Classification of degenerative arthritis

N S Mitchell, R L Cruess

    Canadian Medical Association Journal
    |October 8, 1977
    PubMed
    Summary

    Degenerative arthritis may develop from abnormal forces on cartilage or bone. A new classification system focuses on these mechanical factors, moving beyond traditional disease-based categories for osteoarthritis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Teaching professionalism - Why, What and How.

    Facts, views & vision in ObGyn·2014
    Same author

    Medical professionalism: another view.

    Health affairs (Project Hope)·2001
    Same author

    Professionalism: an ideal to be sustained.

    Lancet (London, England)·2000
    Same author

    Professionalism and medicine's social contract.

    The Journal of bone and joint surgery. American volume·2000
    Same author

    Medical professionalism in society.

    The New England journal of medicine·2000
    Same author

    Professionalism: a contract between medicine and society.

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2000

    Area of Science:

    • Orthopedics
    • Biomechanical Engineering
    • Rheumatology

    Background:

    • Traditional classifications of degenerative arthritis, such as osteoarthritis, distinguish between idiopathic and secondary types.
    • Recent research highlights the critical role of mechanical forces in the pathogenesis of degenerative joint diseases.

    Purpose of the Study:

    • To propose a novel classification system for degenerative arthritis based on biomechanical principles.
    • To challenge the existing dichotomy of idiopathic versus secondary degenerative arthritis.

    Main Methods:

    • Review of recent studies on the etiology of degenerative arthritis.
    • Development of a new classification framework based on force concentrations and cartilage/bone matrix properties.

    Main Results:

    • The established division of degenerative arthritis is potentially outdated.
    • Degenerative arthritis can be initiated by abnormal forces on normal cartilage, normal forces on abnormal cartilage, or normal forces on cartilage overlying abnormal bone.

    Conclusions:

    • A biomechanically-driven classification offers a more accurate understanding of degenerative arthritis.
    • This new framework may guide future research and therapeutic strategies for osteoarthritis.

    Related Experiment Videos