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Ambulatory mediastinal biopsy for hematologic malignancies

F Venuta1, E A Rendina, E O Pescarmona

  • 1Department of Thoracic Surgery, University of Rome La Sapienza, Italy.

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|February 1, 1997
PubMed
Summary

Outpatient surgical biopsy of mediastinal lesions in patients with hematologic malignancies is safe and effective for diagnosis. This approach significantly reduces costs compared to inpatient procedures.

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Area of Science:

  • Oncology
  • Surgical Pathology
  • Hematology

Background:

  • Mediastinal lesions are common in patients with hematologic malignancies.
  • Accurate diagnosis is crucial for effective treatment planning.

Purpose of the Study:

  • To evaluate the safety, diagnostic yield, and cost-effectiveness of outpatient surgical biopsy for mediastinal lesions in patients with hematologic malignancies.

Main Methods:

  • Retrospective review of 80 patients undergoing outpatient surgical biopsy (cervical mediastinoscopy, anterior mediastinotomy, video-assisted thoracoscopy).
  • Analysis of diagnostic accuracy, complications, and costs compared to inpatient procedures.

Main Results:

  • Outpatient biopsy achieved a diagnosis in all cases.

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  • Common diagnoses included Hodgkin disease and non-Hodgkin lymphoma.
  • No operative mortality was observed; complications were minor and manageable.

    • Conclusions:

    • Outpatient surgical biopsy is a safe and effective method for diagnosing mediastinal involvement in hematologic malignancies.
    • This approach offers significant cost savings over inpatient procedures.