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Interactions between enteropathogenic Escherichia coli and host epithelial cells
M S Donnenberg1, J B Kaper, B B Finlay
1Divn of Infectious Diseases, University of Maryland School of Medicine, Baltimore 21201, USA. mdonnenb@umabnet.ab.umd.edu
Trends in Microbiology
|March 1, 1997
Abstract:
The pathogenesis of enteropathogenic Escherichia coli (EPEC) infection is emerging as a paradigm for a multistage microorganism-host cell interaction. Both type IV fimbriae and a type III secretion apparatus play principal roles in interactions between the bacteria and host cells. Recent data suggest that bacteria-induced signal transduction activates the receptor that allows tenacious adherence of the bacteria to the host cell surface.