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[Endovascular occlusion of intracranial aneurysms using the "Guglielmi Detachable Coil"]
H J Nepper-Rasmussen1, P K Bjerre, P B Andersen
1Universitetshospital, Røntgendiagnostisk Afdeling og Neurokirurgisk Afdeling.
Insights
Endovascular occlusion using Guglielmi Detachable Coils (GDC) is a promising treatment for delicate intracranial aneurysms. This innovative procedure achieved successful occlusion in most patients, with a low rate of major complications.
Area of Science:
- Neurosurgery
- Interventional Neuroradiology
- Vascular Neurology
Background:
- Intracranial aneurysms, particularly those in delicate locations, pose significant treatment challenges.
- Traditional surgical approaches may carry high risks for these complex cases.
Purpose of the Study:
- To evaluate the safety and efficacy of endovascular occlusion with Guglielmi Detachable Coils (GDC) for sacculate intracranial aneurysms in delicate locations.
Main Methods:
- Thirty-seven patients with 42 aneurysms were treated or attempted treatment with GDC between July 1994 and December 1995.
- Aneurysm occlusion was assessed, and follow-up angiography was performed at six months postoperatively.
Main Results:
- Successful occlusion was achieved in 35 of 42 aneurysms (31 patients).
- Five aneurysms were not occluded due to unfavorable anatomy, and two procedures were interrupted due to complications.
- Two patients experienced major complications (mortality), and five had minor complications; 39 procedures were uncomplicated.
Conclusions:
- Endovascular occlusion with GDC is a promising and innovative therapeutic option for intracranial aneurysms in delicate locations.
- The procedure demonstrates a favorable outcome profile, with successful occlusion and manageable complication rates.
Abstract:
Thirty-seven patients with 42 sacculate intracranial aneurysms of delicate location were treated, or attempted treated, with Guglielmi Detachable Coils (GDC) from July 1994 through December 1995. Intended aneurysm occlusion was not achieved in five patients (five aneurysms) due to unfavourable anatomy. In two additional cases the procedure was interrupted because of complications. In 31 patients (35 aneurysms) the aneurysms were successfully occluded. So far 16 patients (19 aneurysms) have undergone angiography six months postoperatively, and four of five partly recanalized aneurysms were reoccluded. Two patients died following a major complication, and five patients recovered following a minor complication to the procedure. A total of 39 procedures were uncomplicated, and the patients recovered uneventfully. In conclusion, endovascular occlusion with GDC of intracranial aneurysms of delicate location is a promising innovative procedure.