Related Experiment Videos
Histopathological comparison between tonsil and adenoid responses to allergy
L H Endo1, A Altemani, C Chone
1Department of Pathologic Anatomy, State University of Campinas, Sao Paulo, Brazil.
Acta Oto-Laryngologica. Supplementum
|January 1, 1996
Summary
Allergic children exhibit significant differences in palatine tonsil and adenoid histopathology, particularly in edema and epithelial structure. These findings suggest distinct tissue responses to allergens in the upper airway.
Area of Science:
- Immunology
- Otorhinolaryngology
- Pathology
Background:
- Previous research indicated edema in the chorium of adenoid tissue in 80.4% of allergic children.
- Antihistamine treatment showed potential in reducing adenoid edema in allergic children.
Purpose of the Study:
- To compare the histopathology of palatine tonsils and adenoids in allergic patients.
- To analyze edema intensity and cellular components in the chorium of these tissues.
Main Methods:
- Histopathological analysis of 56 palatine tonsils and 97 adenoids from 153 allergic children.
- Assessment of edema and cellular infiltration in the chorium of both tissue types.
Main Results:
- Edema was frequently observed in adenoids, with a significantly different presentation compared to tonsils.
- Palatine tonsils displayed thicker squamous epithelium with stronger intercellular junctions than adenoid columnar epithelium.
- Differences in epithelial structure may impede antigen contact with the chorium in tonsils.
Conclusions:
- Histopathological differences exist between allergic palatine tonsils and adenoids, particularly regarding edema and epithelial characteristics.
- The structural integrity of tonsillar squamous epithelium may offer a barrier against antigen penetration compared to adenoid columnar epithelium.