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Lidocaine-induced CNS toxicity--a case report
Y Y Chiang1, K F Tseng, Y W Lih
1Department of Anesthesiology, Taipei Municipal Yang Ming Hospital, Taiwan, R.O.C.
Summary
Lidocaine (a common local anesthetic) can cause central nervous system (CNS) intoxication, even in healthy individuals, manifesting as psychotic reactions. This case highlights the importance of careful dosing and awareness of potential lidocaine toxicity during medical procedures.
Area of Science:
- Anesthesiology
- Toxicology
- Pharmacology
Background:
- Lidocaine is a widely used amide-type local anesthetic known for its efficacy and safety.
- Despite its safety profile, systemic intoxication and psychotic reactions can occur, often due to ignored usage guidelines and overdose.
- Recent reports on lidocaine's toxic reactions are infrequent despite its universal application.