Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Arousals in infants

B T Thach1, A Lijowska

  • 1Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

Sleep
|December 1, 1996
PubMed
Summary
This summary is machine-generated.

Infant arousal involves a sigh, startle, and thrashing sequence. This reflex sequence protects airways during mild asphyxia, crucial for infant survival.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Response by Bradley Thach.

Journal of perinatology : official journal of the California Perinatal Association·2014
Same author

Deaths and near deaths of healthy newborn infants while bed sharing on maternity wards.

Journal of perinatology : official journal of the California Perinatal Association·2014
Same author

Recurrent laryngeal nerve injury during patent ductus ligation: can this common complication be reduced?

Journal of perinatology : official journal of the California Perinatal Association·2010
Same author

Sex-specific quantitative trait loci linked to autoresuscitation failure in SWR/J mice.

Heredity·2009
Same author

Laryngeal constriction during hypoxic gasping and its role in improving autoresuscitation in two mouse strains.

Journal of applied physiology (Bethesda, Md. : 1985)·2009
Same author

Maturation and transformation of reflexes that protect the laryngeal airway from liquid aspiration from fetal to adult life.

The American journal of medicine·2001
Same journal

Sleep, circadian, and mental health in neurodivergent neurotypes: Lived experience perspective on the research landscape and roadmaps.

Sleep·2026
Same journal

Nighttime light exposure is associated with metabolic dysfunction in schizophrenia: A cross-sectional analysis of the LENS study.

Sleep·2026
Same journal

Sleep Need Outcompetes Preparation: Reframing Sleep Initiation Through Naturalistic Behaviour.

Sleep·2026
Same journal

The Quest for Automated Pediatric Sleep Scoring: Are We There Yet?

Sleep·2026
Same journal

Sex Differences in the Sleep Architecture and Sleep-Disordered Breathing in C57BL/6 J Mice.

Sleep·2026
Same journal

Differential Effects of Prenatal Depression and Anxiety on Infant Sleep: Dual-Pathway Mechanisms Involving the HPA Axis and the Gut-Brain Axis.

Sleep·2026
See all related articles

Area of Science:

  • Neonatal physiology
  • Sleep studies
  • Respiratory reflexes

Background:

  • Infant arousal from sleep is a complex process.
  • Specific reflex sequences precede full behavioral arousal.

Purpose of the Study:

  • To characterize the sequence of reflex responses during stimulus-induced arousal in young infants.
  • To investigate the airway protective function of these arousal components.

Main Methods:

  • Polygraphic recordings were used to monitor sleep and arousal.
  • Stimulus-induced arousals were elicited in young infants.
  • Analysis focused on the 2-4 second period before behavioral arousal.

Main Results:

  • A consistent arousal sequence was identified: augmented breath (sigh), sleep startle, and stereotyped motor activity (thrashing).

Related Experiment Videos

  • Partial arousals, including sigh or sigh-startle, were frequently observed.
  • Startle and thrashing demonstrated significant external airway protective function during induced mild asphyxia.
  • Conclusions:

    • The identified arousal sequence plays a vital role in protecting the infant airway.
    • These reflexes are critical for managing respiratory challenges like mild asphyxia.