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Retinal ultrastructure in advanced retinitis pigmentosa
Investigative Ophthalmology & Visual Science
|October 1, 1977
Summary
Advanced retinitis pigmentosa causes orderly cone degeneration, affecting the perifovea more than the fovea. Structural damage in photoreceptors and pigment epithelial cells prevents pinpointing the primary defect site.
Area of Science:
- Ophthalmology
- Cell Biology
- Retinal Degeneration
Background:
- Retinitis pigmentosa (RP) is a group of inherited retinal diseases causing progressive vision loss.
- Ultrastructural changes in advanced RP provide insights into photoreceptor and retinal pigment epithelium (RPE) dysfunction.