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Updated: Aug 18, 2026

Generation of Murine Monoclonal Antibodies by Hybridoma Technology
09:42

Generation of Murine Monoclonal Antibodies by Hybridoma Technology

Published on: January 2, 2017

[An efficient, antigen-saving, labor-saving, and time-saving technique for making monoclonal antibodies with enlarged

Y Sado1, M Kagawa

  • 1Division of Immunology, Shigei Medical Research Institute, Okayama.

Seikagaku. the Journal of Japanese Biochemical Society
|February 1, 1997
PubMed
Abstract

No abstract available in PubMed .

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Hybridoma Technology01:31

Hybridoma Technology

Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation, polyethylene glycol...