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Active efflux of antimicrobial agents in wild-type strains of enterococci
C Lynch1, P Courvalin, H Nikaido
1Department of Molecular and Cell Biology, University of California, Berkeley 94720, USA.
Antimicrobial Agents and Chemotherapy
|April 1, 1997
Abstract:
Enterococci are intrinsically resistant to numerous antimicrobial agents. We examined the energy-dependent efflux of radiolabeled drugs from four reference strains of Enterococcus faecalis and a strain of Enterococcus faecium and found that most strains pumped out norfloxacin and chloramphenicol. Efflux of tetracycline was detected only in certain strains.