Related Experiment Video
Updated: Sep 6, 2026
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
Pattern reversal visual evoked potentials in eyes with macular holes and their fellow eyes
N A Bemelmans1, M A Tilanus, M H Cuypers
1Institute of Ophthalmology, University Hospital Nijmegen, The Netherlands.
Purpose:
To investigate whether the pattern reversal visual evoked potential can be useful in the diagnosis and management of macular hole patients.
Methods:
The pattern reversal visual evoked potential was measured in 66 patients with a macular hole and in 43 healthy control subjects. Check sizes of 34', 17' and 10' were applied.
Results:
Results showed that, for the check sizes of 34', 17' and 10', eyes with a macular hole had significantly prolonged N80 and P100 latencies and a significantly reduced P100 amplitude as compared to their fellow eyes. Furthermore, for the 10' check size, the fellow eyes appeared to have a significantly reduced P100 amplitude in comparison with the control eyes, whereas N80 and P100 latencies of the fellow eyes of the macular hole patients were not prolonged.
Conclusion:
Significant pattern reversal visual evoked potential alterations were shown in eyes with macular holes and fellow eyes for small check sizes.
