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Regional assignment of genetic markers using a somatic cell hybrid panel: a WWW interactive program available for the
C Chevalet1, J Gouzy, M SanCristobal-Gaudy
1Laboratoire de Génétique Cellulaire, Institut National de la Recherche Agronomique BP 27, Tolosan, France. chevalet@toulouse.inra.fr
Computer Applications in the Biosciences : CABIOS
|February 1, 1997
Abstract
Motivation:
Quick and easy gene mapping by the use of a panel of cytogenetically characterized somatic cell hybrids is possible, even if some discordant experimental results arise.
Results:
An interactive program is proposed and is made available on a WWW site to users of a somatic cell hybrid panel. Assignments to chromosomes and subchromosomal regions are based on likelihood calculations and Bayes' theorem, and a confidence level is provided. The method is illustrated in the case of the pig genome.