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Updated: Jul 24, 2026

Solid Plate-based Dietary Restriction in Caenorhabditis elegans
Published on: May 28, 2011
Diet and calorie restriction
1Biology of Aging Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA.
Abstract:
Current data suggest that the life spans of commonly held rodent species have decreased and the occurrence of tumors occurs earlier in the lifespan of ad libitum-fed animals. The most likely cause of this change in the life span of barrier-reared genetically defined animals is increased body weight. The effects of caloric restriction on a variety of functional measures and on age-dependent tumors and lesions are the focus of this presentation. Recommendations for caloric restriction, or at least "dietary control," will be discussed.
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