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Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
Published on: February 5, 2018
A color spot test for the detection of Kryptofix 2.2.2 in [18F]FDG preparations
B H Mock1, W Winkle, M T Vavrek
1Department of Radiology, Indiana University Hospital, Indianapolis 46202-5253, USA. BMOCK@xray.indyrad.iupui.edu
Abstract:
A color spot test is described that can confirm the absence of Kryptofix 2.2.2 in 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) in less than 5 min. Pretreated strips of plastic-backed silica gel 60 thin-layer chromatographic medium, saturated with iodoplatinate reagent, are over-spotted with separate droplets of final product [18F]FDG and Kryptofix standard solutions. A blue-black circular spot is clearly visible at Kryptofix concentrations as low as 2 micrograms/mL.
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