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Topical anaesthesia for diagnostic hysteroscopy and endometrial biopsy in postmenopausal women: a randomised
E Cicinelli1, T Didonna, G Ambrosi
1Department of Obstetrics and Gynecology, University of Bari, Italy.
Objective:
To evaluate the efficacy and safety of topical anaesthesia in reducing pain and incidence of vasovagal reactions during diagnostic hysteroscopy with endometrial biopsy in postmenopausal women.
Design:
Randomised placebo-controlled double-blind study.
Setting:
University hospital.
Participants:
Eighty postmenopausal women undergoing diagnostic hysteroscopy and endometrial biopsy.
Interventions:
Two millilitres of 2% mepivacaine or saline solution were injected transcervically into the uterine cavity before performing the procedures.
Main Outcome Measures:
Evaluation of pain reduction on a visual analogue scale and continuous monitoring of heart rate and blood pressure.
Results:
The use of the anaesthetic significantly reduced the pain experienced at hysteroscopy and endometrial biopsy. The occurrence of vasovagal reactions was significantly lower in the anaesthetised group.
Conclusions:
Topical anaesthesia attenuated pain and effectively prevented the occurrence of vasovagal reactions during hysteroscopy and endometrial biopsy in postmenopausal women.