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[Effect of anthocyanins on human connective tissue metabolism in the human]
1Labor für Bindegewebsbiochemie, Medizinische Fakultät, Universität Paris, Val de Marne.
Background:
Diabetic retinopathy can lead to blindness. This is due to an abnormally increased synthesis of connective tissue in order to a) repair leaking capillaries and b) formation of new capillaries.
Method:
Twelve adult diabetics were treated with 600 mg anthocyanosides per day for two months. Samples of gingiva tissue were taken before and after treatment. Incubated with radio-active labeled amino acids, the measure of radioactivity from different connective tissue extracts can show a changed protein biosynthesis activity.
Results:
The use of radio-active labeled amino acids show significant decrease of biosynthesis-activity of connective tissue especially polymeric collagen and structure-glycoproteins by anthocyanoside medication.
Conclusions:
Anthocyanosides help to prevent diabetics from injuries caused by malfunction of synthesis-activities throughout normal diabetic medical treatment.
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