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Anti-M and anti-N reactivity with Tn and T activated cells
1Pacific Northwest Region-American Red Cross, Portland, OR 97227, USA.
Abstract:
Monoclonal (MoAB) anti-N and anti-M were tested against normal, T-activated, and Tn-activated RBCs. In vivo T and Tn activation affects the sialic acid expression on the RBCs which may affect the binding of antibodies to the M and/or N antigens. The majority of MoAB anti-M and anti-N in this workshop demonstrated some effect from in vivo T and Tn activation.