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Studies on section 2D3 monoclonal antibodies

E A Smart1, V Reddy

  • 1Natal Blood Transfusion Service, Pinetown, South Africa.

Monoclonal antibodies (MAbs) directed against CD-related antigens were tested with various red cell samples from different ethnic groups in KwaZulu-Natal. The MAbs were tested by standard red cell serological techniques. The MAbs with specificities CD44, CD58 and RBC, reacted with all the samples tested. CD99 was non-reactive. The two Rh?related MAbs showed possible Rh specificity by saline technique, as did one CD47, MAb 2D3-6.

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