Gingival vascular hamartoma with associated paraneoplastic hyperglycemia in a kitten

A 4-month-old domestic shorthair cat was examined because of a maxillary gingival mass that had regrown following excisional biopsy. The kitten also had a history of persistently high blood glucose concentrations, despite 2 weeks of insulin treatment. Radiography revealed maxillary alveolar bone lysis and displacement of multiple teeth. Partial maxillectomy was performed to remove the mass, which histologically was a gingival vascular hamartoma. Hyperglycemia permanently resolved < 24 hours after mass removal. On the basis of the temporal relationship between mass removal and resolution of hyperglycemia, as well as the lack of evidence of any concurrent disease, hyperglycemia in this cat was considered to be a paraneoplastic syndrome.