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Does angiotensin play a role in human fetal erythropoiesis?
E M Anderson1, D R Jones, D T Liu
1Department of Immunology, Queen's medical Centre, Nottingham, UK.
Biology of the Neonate
|January 1, 1997
Abstract:
Angiotensin affects the growth of many cell types and there have been suggestions that it could influence cells which respond to erythropoietin. During first trimester, human fetal haematopoietic cells are exquisitely responsive to erythropoietin and we have assessed the potential for angiotensin to also influence the growth of these cell types in a standard culture system. The data obtained from these studies indicate that angiotensin does not influence fetal haematopoiesis over a range of concentrations.