Norepinephrine, dopamine and serotonin in experimental spinal cord trauma: current status

The status and function of monoamines in experimental spinal cord trauma remains a subject of controversy and continued debate. The norepinephrine hypothesis has been severely weakened by its lack of reproducibility. Dopamine results are too variable to draw meaningful conclusions. The role of serotonin, particularly with reference to its vasoactive properties and the physiological importance of its effects, remains to be determined.