Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Drug-induced depression

S B Patten1, E J Love

  • 1Department of Community Health Sciences, University of Calgary, Canada.

Psychotherapy and Psychosomatics
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

Certain medications can cause depression, with strong evidence for corticosteroids, calcium channel blockers, and digoxin. Drug-induced depression is a growing area of research, but current diagnostic categories may not fully align with the evidence.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal study examining the relationship between physical activity and psychiatric hospitalizations in canadian adolescents and young adults utilizing record linkage.

Scientific reports·2024
Same author

The factor structure of the Patient Health Questionnaire-9 in stroke: A comparison with a non-stroke population.

Journal of psychosomatic research·2024
Same author

Prevalence of Common Child Mental Health Disorders Using Administrative Health Data and Parent Report in a Prospective Community-Based Cohort from Alberta, Canada: Prévalence des troubles communs de santé mentale de l'enfant à l'aide des données de santé administratives et des rapports des parents dans une cohorte prospective communautaire d'Alberta, Canada.

Canadian journal of psychiatry. Revue canadienne de psychiatrie·2024
Same author

Understanding the impact of COVID-19 isolation measures on individuals with mood disorders in mental health clinics.

Journal of affective disorders reports·2022
Same author

Depression as a risk factor for the development of psoriasis: a retrospective cohort study in the UK.

The British journal of dermatology·2020
Same author

Safety of psychotropic medicines: looking beyond randomised evidence.

Epidemiology and psychiatric sciences·2018
Same journal

Schizophrenia Genetic Liability Drives Chronic Disease Risk in Unaffected Individuals Through Immune and Metabolic Pathways.

Psychotherapy and psychosomatics·2026
Same journal

Psychotherapy, Antidepressants, and Combined Treatment for Depression: A Network Meta-analysis on Social Functioning Outcomes.

Psychotherapy and psychosomatics·2026
Same journal

Ketamine-assisted psychotherapy for posttraumatic stress disorder: a systematic review and individual participant data meta-analysis of predictors of treatment effects.

Psychotherapy and psychosomatics·2026
Same journal

Clarifying Scope and Interpretation of Psychotherapeutic Consultation at Work: A Response to Recent Commentary.

Psychotherapy and psychosomatics·2026
Same journal

Efficacy and Moderators of Mindfulness-Based Cognitive Therapy in Difficult-to-Treat Depression: A Systematic Review and Individual Participant Data Meta-Analysis.

Psychotherapy and psychosomatics·2026
Same journal

Does fatigue in patients with Post-COVID-19 Syndrome improve with rehabilitation?

Psychotherapy and psychosomatics·2026
See all related articles

Area of Science:

  • Pharmacology
  • Psychiatry
  • Clinical Medicine

Background:

  • Medications can play a role in the development of depressive symptoms and disorders.
  • Understanding drug-induced depression is crucial for accurate diagnosis and treatment.

Purpose of the Study:

  • To critically review existing literature on the association between drug exposure and depressive symptoms.
  • To identify specific drug classes with a confirmed or potential link to depression.

Main Methods:

  • Comprehensive literature search using Medline, Psychlit, and Psychological Abstracts.
  • Analysis of case reports and empirical studies.
  • Statistical power calculations to interpret negative findings.

Main Results:

Related Experiment Videos

  • Strong evidence links corticosteroids, calcium channel blockers, and digoxin to depression.
  • Psychostimulant withdrawal is associated with depressive symptoms.
  • Preliminary evidence suggests links for antihyperlipidemic agents, ACE inhibitors, and others; beta-blocker association remains controversial.

Conclusions:

  • A growing body of evidence supports the role of certain drugs in the etiology of depression.
  • Current classification of Substance-Induced Mood Disorder may not be fully supported by the literature.