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Submacular hemorrhage removal

J I Lim1, C Drews-Botsch, P Sternberg

  • 1Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA 30322, USA.

Ophthalmology
|September 1, 1995
PubMed
Summary
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Pars plana vitrectomy with tissue plasminogen activator can improve vision after submacular hemorrhage. However, final visual acuity is often limited by the underlying cause of the bleed.

Area of Science:

  • Ophthalmology
  • Retinal Surgery

Background:

  • Submacular hemorrhage (SMH) poses a significant threat to visual acuity.
  • Effective surgical strategies are crucial for managing SMH and improving patient outcomes.

Purpose of the Study:

  • To evaluate the efficacy of pars plana vitrectomy (PPV) combined with tissue plasminogen activator (tPA) for submacular hemorrhage evacuation.
  • To assess the impact of this combined approach on visual acuity outcomes.

Main Methods:

  • Retrospective review of 18 patients undergoing PPV with subretinal tPA injection for dense SMH.
  • Analysis of preoperative and postoperative visual acuity, diagnoses, and follow-up duration.

Main Results:

  • The primary diagnoses were age-related macular degeneration (16 patients).

Related Experiment Videos

  • Sixty-one percent (11/18) of patients experienced a two-line or more improvement in best-corrected visual acuity post-surgery.
  • Final visual acuity outcomes were influenced by the underlying pathology, with 39% showing a decrease of two or more lines.

    • Conclusions:

    • Pars plana vitrectomy combined with tPA is a viable option for evacuating massive subretinal hemorrhages.
    • While the procedure can improve visual acuity, the ultimate visual outcome is often dictated by the pre-existing ocular condition.