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Stevens-Johnson syndrome associated with methazolamide treatment reported in two Japanese-American women
A J Flach1, R E Smith, F T Fraunfelder
1University of California, San Francisco Medical Center, Department of Ophthalmology, Corte Madera 94976, USA.
Background:
Systemic acetazolamide treatment has been reported in association with Stevens-Johnson syndrome (SJS). This is the first report of this syndrome associated with methazolamide treatment. The association is reported in two Japanese-American women.
Method And Results:
Two patients with SJS, which developed during treatment with methazolamide, are described. Other potential associations are discussed.
Conclusions:
Systemically administered carbonic anhydrase inhibitors, including both acetazolamide and methazolamide can be associated with SJS.
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