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Soluble CD30 serum antigen in Kawasaki disease
C Vagliasindi1, F Spinozzi, L Sensi
1Department of Paediatrics and Internal Medicine and Oncological Sciences, Perugia University Medical School, Italy.
Acta Paediatrica (Oslo, Norway : 1992)
|March 1, 1997
Abstract:
Very high levels of sCD30, a glycoprotein surface antigen expressed by T lymphocytes and other mononuclear cells of the immune system, were found in serum samples from 10 children with typical Kawasaki disease (KD), but not in blood specimens from a vast cohort of paediatric control subjects. These data strongly support an involvement of CD30 T cells in the immune processes which take place at the level of lymphoid organs during the acute phase of KD.