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Spiking fevers with clozapine treatment
F Trémeau1, S C Clark, D Printz
1Department of Clinical Psychobiology, New York State Psychiatric Institute, New York 10032, USA.
Clinical Neuropharmacology
|April 1, 1997
Abstract:
Clozapine often causes low-grade fever and less frequently spiking fever. We describe three cases of spiking fever that occurred in the first 3 weeks of clozapine therapy. A new set of side effects of clozapine is identified, which includes spiking fever, respiratory and gastrointestinal symptoms, and neutrophilia. Possible mechanisms are discussed.