Related Experiment Videos
The human gene encoding FKBP-rapamycin associated protein (FRAP) maps to chromosomal band 1p36.2
N J Lench1, R Macadam, A F Markham
1Molecular Medicine Unit, University of Leeds, St. James's University Hospital, UK. desnl@stjames.leeds.ac.uk
Human Genetics
|April 1, 1997
Abstract:
FKBP-rapamycin associated protein (FRAP) is a phosphatidylinositol kinase (PIK)-related kinase implicated in the inhibition of progression through G1 of the cell cycle. The PIK-related kinases are a growing family of proteins involved in cell-cycle checkpoints, DNA repair and recombination. We have mapped the human FRAP gene to chromosome 1p36.2, a region consistently deleted in neuroblastomas.