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90K (Mac-2 BP) in human milk

N D'Ostilio1, G Sabatino, C Natoli

  • 1Cattedra di Oncologia Medica, Università G. D' Annunzio, Chieti, Italy.

Clinical and Experimental Immunology
|June 1, 1996
PubMed

Human 90K, also known as Mac-2 binding protein (Mac-2 BP), is a secreted glycoprotein which is widely expressed, binds to the human macrophage-associated lectin Mac-2, and may have a role in host defence. We have measured the concentrations of 90K in human breast milk from eight healthy mothers delivering mature healthy infants after full-term pregnancy using a specific immunoenzymatic assay. Maximal 90K concentrations were observed on days 2-3 post-partum, and ranged from 13.4 to 79.2 microg/ml. The concentrations of 90K in the milk had no correlation with those in the maternal blood.

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