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Rising serum values of beta-subunit human chorionic gonadotrophin (hCG) in patients with progressive vulvar
H W de Bruijn1, K A ten Hoor, M Krans
1Department of Obstetrics and Gynaecology, University Hospital Groningen, The Netherlands.
British Journal of Cancer
|January 1, 1997
Abstract:
Elevated serum levels of the beta-subunit of human chorionic gonadotrophin (hCG) were measured in 50% of patients with locoregional recurrences or progressive vulvar carcinoma (n = 14). At diagnosis of vulvar cancer, however, the incidence of elevated serum levels was low (5%) in 104 patients. The rising serum levels during progression of disease indicate that the synthesis of the beta-subunit hCG can be increased in vulvar carcinoma.