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Related Experiment Videos

Prenatal diagnosis in Denmark

C Lundsteen1, L O Vejerslev

  • 1Department of Clinical Genetics, Juliane Marie Centre, Rigshospitalet, Copenhagen, Denmark.

European Journal of Human Genetics : EJHG
|January 1, 1997
PubMed
Summary
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Prenatal diagnosis in Denmark monitors over 10% of pregnancies using amniocentesis or chorionic villus sampling. The Danish Central Cytogenetic Register tracks these tests for genetic counseling and public health oversight.

Area of Science:

  • Medical Genetics
  • Public Health
  • Reproductive Medicine

Background:

  • Denmark's prenatal diagnosis (PND) system involves 5 genetic departments.
  • Over 10% of pregnancies undergo monitoring via amniocentesis (AC) or chorionic villus sampling (CVS).
  • Prenatal cytogenetic analyses are centrally registered in the Danish Central Cytogenetic Register (DCCR).

Purpose of the Study:

  • To provide information for genetic counseling.
  • To enable health authorities to monitor PND services.
  • To outline current PND procedures and emerging technologies.

Main Methods:

  • Amniocentesis (AC)
  • Chorionic villus sampling (CVS)
  • Chordocentesis
  • Ultrasound scan

Related Experiment Videos

  • Cytogenetic, molecular, and biochemical analyses
  • Investigational methods: Fluorescent in situ hybridisation (FISH), comparative genomic hybridisation (CGH), and fetal cells in maternal blood.

    • Main Results:

    • Approximately 40% of trisomy 21 cases are diagnosed prenatally.
    • PND is a publicly funded health service, with expenses covered by counties.
    • Legislation currently prohibits pre-implantation diagnosis.

    Conclusions:

    • Clinical genetics is now a registered medical specialty in Denmark.
    • The DCCR is crucial for PND data management and public health monitoring.
    • Ongoing research explores advanced diagnostic techniques for prenatal screening.