Prenatal diagnosis in the United Kingdom--an overview

Prenatal diagnosis is now a well-established part of health care in the UK. Cytogenetic or molecular diagnostic analysis following amniocentesis, chorionic villus sampling or cordocentesis is in routine practice and identification of 'at risk' pregnancies using biochemical screening or ultrasound is widespread. Professional guidelines have been established covering both sampling procedures and diagnostic testing, and legislation is in place regarding termination of pregnancy and pre-implantation diagnosis. The close liaison of the various groups of professionals involved has led to well-developed prenatal diagnostic and screening services within the UK. These links have been the major contributory factor to the current state of prenatal diagnosis and have been of great benefit to patients undergoing prenatal testing.