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Malignancy in patients with rheumatoid arthritis treated with methotrexate

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IL-33 is expressed in human osteoblasts, but has no direct effect on bone remodeling.

TNF-α stimulates alkaline phosphatase and mineralization through PPARγ inhibition in human osteoblasts.

Do cytokines induce vascular calcification by the mere stimulation of TNAP activity?

TNF-alpha and IL-1beta inhibit RUNX2 and collagen expression but increase alkaline phosphatase activity and mineralization in human mesenchymal stem cells.

Gene expression in normotopic and heterotopic human bone: increased level of SP7 mRNA in pathological tissue.

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