Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[pHi value as a prognostic parameter in septic and polytrauma patients]

J Weitz1, P Kienle, H Schmidt

  • 1Chirurgische Klinik, Ruprecht-Karls-Universität, Heidelberg.

Langenbecks Archiv Fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft Fur Chirurgie. Kongress
|January 1, 1996
PubMed
Summary

Gastric mucosal pH (pHi) is a significant prognostic indicator in trauma patients and critically ill septic shock patients. A low pHi in septic shock patients indicates a poor prognosis, suggesting other factors influence gut oxygenation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Detection of isolated disseminated tumor cells in bone marrow and blood samples of patients with hepatocellular carcinoma.

Archives of surgery (Chicago, Ill. : 1960)·2000
Same author

[More attention to hernia surgery!].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2000
Same author

Sequential (domino) transplantation of the liver in a transthyretin-50 familial amyloid polyneuropathy. Special reference to cardiological diagnosis and complications.

Langenbeck's archives of surgery·2000
Same author

Spectrometry supports fluorescence staging laparoscopy after intraperitoneal aminolaevulinic acid lavage for gastrointestinal tumours.

Journal of photochemistry and photobiology. B, Biology·2000
Same author

Expression of cytokeratin 20 in thyroid carcinomas and peripheral blood detected by reverse transcription polymerase chain reaction.

British journal of cancer·2000
Same author

Development of a computer based training program for liver transplantation.

Transplantation proceedings·2000

Area of Science:

  • Critical Care Medicine
  • Gastroenterology
  • Physiology

Context:

  • Sepsis and trauma are leading causes of critical illness.
  • Gastric mucosal pH (pHi) is a potential indicator of gut mucosal oxygenation.
  • Systemic oxygen transport parameters are crucial in managing critically ill patients.

Purpose:

  • To evaluate the prognostic significance of gastric mucosal pH (pHi) in patients with septic shock and severe trauma.
  • To determine the relationship between gastric mucosal oxygenation and systemic oxygen transport parameters.

Summary:

  • Gastric mucosal pH (pHi) was measured in 17 septic shock and 12 trauma patients (ISS > or = 20).
  • In trauma patients, initial pHi showed high prognostic significance (survivors: 7.38 vs. non-survivors: 7.15, p < 0.05).

Related Experiment Videos

  • In septic shock, no patient with a pathologic pHi (< 7.35) survived beyond 12 hours.

    • Impact:

    • Gastric mucosal pH (pHi) is a valuable prognostic marker in trauma and septic shock.
    • No correlation was found between pHi and systemic oxygen transport, indicating other factors are critical for gut mucosal oxygenation.
    • Findings suggest a need to explore additional mechanisms beyond systemic oxygen delivery impacting gastric mucosal perfusion in critical illness.