Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Principles of radical surgery]

J R Siewert1

  • 1Chirurgische Klinik und Poliklinik, Technische Universität München.

Langenbecks Archiv Fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft Fur Chirurgie. Kongress
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Influence of hospital volume on local recurrence and survival in a population sample of rectal cancer patients.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2005
Same author

[Abdomino-right-thoracic esophagectomy with intrathoracic anastomosis in Barrett's cancer].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2005
Same author

[Patient safety in view of specialization, minimum quantity and regionalization].

Deutsche medizinische Wochenschrift (1946)·2005
Same author

[Reoperation for thyroid cancer].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2005
Same author

[Barrett's esophagus].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2004
Same author

Malignant degeneration of Barrett's esophagus: the role of the Ki-67 proliferation fraction, expression of E-cadherin and p53.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2004
Same journal

[[Systemic genotoxic effect caused by ischemia-/reperfusion-/surgical trauma of the lower extremity--detection of DNA chain breaks in leukocytes with the Comet Assay]].

Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress·2018
Same journal

[Reduction of cardiovascular disorders by preventive perioperative antihistamine administration in general surgery: are the drugs interchangeable?].

Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress·2003
Same journal

[Reduction of local and systemic complications of acute pancreatitis by monoclonal antibody to ICAM-1].

Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress·2003
Same journal

[Changes in permeability after ileoanal pouch anastomosis and in pouchitis].

Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress·2003
Same journal

[Heterologous transplantation of human parathyroid glands after microencapsulation with clinically suitable alginate : long-term function without immunosuppression in the animal model].

Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress·2003
Same journal

[Effect of humanised anti-L- selectin antibody HuDreg 200 on leukocyte kinetics in pulmonary microcirculation in endotoxinemia].

Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress·2003
See all related articles

Achieving surgical radicality, defined by tumor-free margins and favorable lymph node ratios, is crucial for cancer patient healing. Preoperative therapy can help achieve radicality in advanced stages, with pathology confirming the outcome.

Area of Science:

  • Oncologic surgery
  • Surgical pathology

Context:

  • Radicality is the primary goal in oncologic surgery for patient healing.
  • Defining and objectifying radicality is essential for treatment planning and evaluation.

Purpose:

  • To define the criteria for surgical radicality in oncologic surgery.
  • To outline the role of lymph node status and preoperative therapy in achieving radicality.
  • To emphasize the pathologist's role in objectifying postoperative radicality.

Summary:

  • Surgical radicality involves achieving tumor-free margins in all three dimensions, including the tumor bed.
  • A favorable lymph node ratio, ideally below 0.2, is critical for improved prognosis.
  • Preoperative multimodal therapy can be employed for advanced tumors to potentially achieve radicality in responders.

Related Experiment Videos

  • Postoperative assessment by a pathologist is crucial for objectifying radicality and guiding further treatment.

    • Impact:

    • Establishes clear, objective criteria for surgical success in cancer treatment.
    • Highlights the importance of multidisciplinary approaches, including neoadjuvant therapy and pathology review.
    • Provides a framework for evaluating treatment effectiveness and improving patient outcomes in oncologic surgery.