Related Experiment Video
Updated: Aug 8, 2026

A Quantitative Assay for Insulin-expressing Colony-forming Progenitors
Published on: November 28, 2011
Abstract:
When a medical problem is studied intensively by several investigators in the world, a solution may sometimes be found simultaneously in different countries. Seventy-five years after the discovery of insulin, the chronology of this event can be reconsidered objectively and the role of each of the protagonists evaluated. The stubbornness of Banting and Best, the technical abilities of Collip and the active support of Macleod were determinant in the use of insulin for the treatment of diabetic patients. Moreover, in the long line of experimentalists and physicians, Lancereaux and Paulesco also deserve special mention.
Related Concept Videos
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion
Insulin and C-peptide are co-secreted in...
Insulin: The Receptor and Signaling Pathways
Insulin: Biosynthesis, Chemistry, and Preparation
Damage or functional impairment of β-cells inhibits insulin production, leading to diabetes. Diabetes treatment primarily uses...
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Diabetes Mellitus: Introduction
Type I Diabetes I: Introduction

