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Factors affecting survival after excision of the rectum for cancer: a multivariate analysis
E L Bokey1, P H Chapuis, O F Dent
1Department of Colon and Rectal Surgery, University of Sydney at Concord Hospital, New South Wales, Australia.
Purpose:
The aim of this study was to identify and categorize the independent prognostic effects of patient, clinical, operative, and pathology variables on long-term survival after anterior resection or abdominoperineal excision of the rectum for cancer.
Methods:
Proportional hazards regression analysis was used to analyze prospective data from 709 patients who underwent surgery at Concord Hospital during a 23-year period. No patient received adjuvant therapy.
Results And Conclusions:
After adjusting for age and clinicopathologic stage, significantly poorer survival was experienced by males, patients with extensive tumor adherent to other organ(s), those with a high-grade tumor or a tumor showing venous invasion, those who had a postoperative cardiovascular or respiratory complication, and those who did not undergo surgery by a colorectal surgeon specialist. The nature of the operation performed had no independent effect on survival.