The biogenesis, traffic, and function of the cystic fibrosis transmembrane conductance regulator

T Jilling1, K L Kirk

  • 1Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham 35294, USA.

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Transport Across the Golgi01:26

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While it is unclear how molecules move between adjacent Golgi cisternae, it is apparent that the molecules move from cis- cisterna, the entry face, to the trans- cisterna, the exit face. Experiments initially suggested vesicles that bud from one cisterna and fuse with the next cisterna to transport proteins between the cisternae. This vesicular transport model describes the Golgi apparatus as a relatively static structure with a unique enzyme composition in each cisterna. Molecules are...
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