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[Kidney transplantation in children]
A Peco-Antić1, M Popović-Rolović, M Bjuik
1University Children's Hospital, Belgrade.
Srpski Arhiv Za Celokupno Lekarstvo
|January 1, 1996
Summary
Kidney transplantation offers improved outcomes for children with end-stage renal disease, with high patient survival rates and good graft function, leading to better psychosocial rehabilitation and fewer growth issues.
Area of Science:
- Pediatric Nephrology
- Transplantation Medicine
Context:
- 174 children with end-stage renal disease (ESRD) received chronic hemodialysis over 14 years.
- Only 35 pediatric patients (20.1%) underwent kidney transplantation.
- Transplantation waiting times averaged 24.6 months, with many procedures performed internationally.
Purpose:
- To evaluate the outcomes of kidney transplantation in pediatric patients with ESRD.
- To assess patient and graft survival rates post-transplantation.
- To analyze long-term graft function, psychosocial status, and growth in transplanted children.
Summary:
- Five-year patient survival was 94.1% and graft survival was 76.4%.
- Post-transplant, 55% achieved a Glomerular Filtration Rate (GFR) >60 ml/min/1.73 m2, indicating good renal function.
- The majority of patients with optimal GFR showed good psychosocial rehabilitation, normal blood pressure, and minimal growth retardation.
Impact:
- Kidney transplantation significantly improves survival and quality of life for children with ESRD.
- Successful transplantation leads to better long-term renal function, psychosocial well-being, and physical development.
- These findings highlight the critical role of transplantation in managing pediatric ESRD and improving patient outcomes.