[Urosepsis]

Septicemia as a result of urinary infection is a serious condition, almost always caused by gram-negative bacteria. The bacterial toxins have a profound influence on haemostasis, microcirculation, and cardiac anf respiratory function. This article contains a brief review of aetiology, pathogenesis, pathophysiology, diagnostic work-up and treatment of this life-threatening condition. As soon as specimens from urine and blood are sent for bacteriological examination, intravenous antibiotics are given. It is essential that free drainage of urine from both kidneys is established by means of a bladder catheter, retrograde catheterization or percutaneous nephrostomy. The development of septic shock is a life-threatening condition which should be treated in an intensive care unit with continuous monitoring of vital parameters.