Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Subacute sclerosing panencephalitis (SSPE)]

K Nihei1

  • 1Department of Neurology, National Children's Hospital.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|April 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multiple intra-articular injections with adipose-derived stem cells for knee osteoarthritis cause severe arthritis with anti-histone H2B antibody production.

Regenerative therapy·2023
Same author

Optimisation of Radiation Therapy in Bladder Preservation Therapy for Patients With Clinical Stage T2N0M0 Bladder Cancer.

Clinical oncology (Royal College of Radiologists (Great Britain))·2022
Same author

Statistical mechanical determination of nanocluster size distributions in the phase coexistence region of a first order phase transition from the isotherms of DMPC monolayers at the air-water interface.

Physical chemistry chemical physics : PCCP·2021
Same author

Antifungal Cyclodepsipeptides, W493 A and B, from Fusarium sp.: Isolation and Structural Determination.

Bioscience, biotechnology, and biochemistry·2016
Same author

Long-term results of salvage photodynamic therapy for patients with local failure after chemoradiotherapy for esophageal squamous cell carcinoma.

Endoscopy·2011
Same author

Submucosal tumor appearance is a useful endoscopic predictor of early primary-site recurrence after definitive chemoradiotherapy for esophageal squamous cell carcinoma.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2010
Same journal

[Development of novel therapeutics for multiple myeloma and improvement of drug lag].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Clinical pharmacy services to patients of immunomodulatory drugs].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Therapeutic drug monitoring of the new anti-myeloma drugs in the treatment of multiple myeloma].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Prognostic value of minimal residual disease assessment using next-generation sequencing in multiple myeloma].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[The evaluation of minimal residual disease in multiple myeloma by an allele-specific oligonucleotide real-time PCR].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Evaluation of minimal residual disease in myeloma by multiparametric flow cytometry].

Nihon rinsho. Japanese journal of clinical medicine·2019
See all related articles

Subacute sclerosing panencephalitis (SSPE) is a rare slow measles virus infection. Diagnosis involves clinical signs and antibody titers, though treatment remains challenging.

Area of Science:

  • Neurology
  • Virology
  • Infectious Diseases

Context:

  • Subacute sclerosing panencephalitis (SSPE) is a severe neurological complication of measles virus infection.
  • Despite decades of research, the exact etiological mechanisms of SSPE remain elusive.
  • While SSPE incidence is declining in Japan, cases persist, with trends showing later onset and altered immune responses.

Purpose:

  • To review the current understanding of Subacute Sclerosing Panencephalitis (SSPE), including its diagnosis and treatment.
  • To highlight the changing epidemiological and clinical features of SSPE.
  • To discuss diagnostic criteria and differential diagnoses for SSPE.

Summary:

  • SSPE is a slow viral infection caused by the measles virus, characterized by specific clinical and laboratory findings.

Related Experiment Videos

  • Diagnostic indicators include clinical presentation, elevated serum and cerebrospinal fluid (CSF) measles antibody titers, and characteristic EEG patterns.
  • Differential diagnoses encompass epilepsy, brain tumors, metabolic disorders, and psychological conditions.

    • Impact:

    • This review provides insights into the evolving nature of SSPE, aiding clinicians in diagnosis and management.
    • Understanding these changes is crucial for effective patient care and public health strategies.
    • The current most effective treatment approach involves a combination of oral inosinpranobex and intrathecal or intraventricular interferon administration.