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[Electron microscopic study of the usual and "minimal forms" of oncornaviruses in human embryonic lung cells
Abstract:
Electron microscopic examinations of KLChKM (human embryo cells spontaneously contaminated with mouse cells) cell cultures revealed extracellular oncornaviruses of A and C types and intracisternal virions of A type which in their submicroscopical organization and morphogenesis were identical to oncornaviruses of mouse L cells. Also "minimal forms" (MiF) of oncornaviruses of A and C types the diameter of which was 30--70 nm were found. MiF of oncornaviruses were found to be formed in the process of budding through the cytoplasmic membrane or membranes of intracellular vacuoles.
Insights
Electron microscopy revealed A and C type oncornaviruses in human embryo cells, identical to mouse oncornaviruses. Minimal forms (MiF) of these viruses were observed budding from cell membranes.
Area of Science:
- Virology
- Cell Biology
- Electron Microscopy