Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Darier's disease associated with multiple café-au-lait macules

V Soroush1, A W Gurevitch

  • 1UCLA School of Medicine, Harbor-UCLA Medical Center, Department of Medicine, Torrance 90509, USA.

Cutis
|April 1, 1997
PubMed
Summary

This study reports the first case of Darier's disease (keratosis follicularis) in a patient with multiple café-au-lait macules. The patient had no prior history of neurofibromatosis, suggesting a potential novel association.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Generalized lichen nitidus: case report and literature review.

Cutis·1999
Same author

A draining tumor in the popliteal fossa.

Archives of dermatology·1999
Same author

Eruptive milia.

Cutis·1997
Same author

Images in clinical medicine. Fish-tank granuloma.

The New England journal of medicine·1997
Same author

Malignant melanoma in a tattoo: case report and review of the literature.

Cutis·1997
Same author

Cutaneous manifestations of disseminated cryptococcosis.

Journal of the American Academy of Dermatology·1995

Area of Science:

  • Dermatology
  • Genetics
  • Oncology

Background:

  • Darier's disease (keratosis follicularis) is an inherited skin disorder with characteristic papules, nail changes, and palmar pits.
  • It is associated with various conditions, including skin cancers and neuropsychiatric disorders.
  • Multiple café-au-lait macules are typically linked to neurofibromatosis.

Observation:

  • A patient presented with multiple café-au-lait macules.
  • The patient had no personal or family history of neurofibromatosis.
  • This patient subsequently developed Darier's disease.

Findings:

  • This case represents the first reported instance of Darier's disease in a patient with multiple café-au-lait macules.
  • The absence of a neurofibromatosis history in this patient is noteworthy.

Related Experiment Videos

  • Highlights a potential, previously undocumented association between these conditions.

    • Implications:

    • Suggests a possible link between genetic factors underlying café-au-lait macules and Darier's disease.
    • May prompt further investigation into shared or interacting pathways.
    • Could influence diagnostic approaches for patients presenting with similar features.