Silicone-associated rheumatic disease: an unsupported myth
1Research Service, Birmingham VA Medical Center, Ala., USA.
Plastic and Reconstructive Surgery
|April 1, 1997
Summary
Extensive research shows no link between silicone breast implants and rheumatic diseases like rheumatoid arthritis or lupus. Controlled studies confirm silicone implants do not cause chronic inflammation or connective tissue diseases.
Area of Science:
- Rheumatology and immunology
- Plastic surgery and reconstructive medicine
Background:
- Anecdotal reports suggested a link between silicone breast implants and rheumatic diseases.
- Previous concerns necessitated rigorous scientific investigation into potential associations.
Purpose of the Study:
- To evaluate the association between silicone breast implants and the development of rheumatic diseases.
- To determine if silicone implants are linked to rheumatoid arthritis, systemic lupus erythematosus, scleroderma, or atypical connective tissue disease.
- To assess the presence of chronic inflammation in patients with silicone breast implants.
Main Methods:
- Systematic review and meta-analysis of controlled studies.
- Analysis of epidemiological data and clinical outcomes.
- Immunological and inflammatory marker assessments in patient cohorts.
Main Results:
- Controlled studies found no association between silicone breast implants and rheumatoid arthritis, systemic lupus erythematosus, or scleroderma.
- Research on "atypical connective tissue disease" also showed no link to silicone implants.
- Multiple controlled studies demonstrated no evidence of chronic inflammation in women with silicone breast implants.
Conclusions:
- Silicone breast implants are not associated with the development of common rheumatic diseases.
- Current evidence refutes a link between silicone implants and atypical connective tissue disease or chronic inflammation.
- These findings should alleviate concerns for women with breast implants and their healthcare providers.
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