[Verrucous malignant melanoma (spontaneous regression and simultaneous development of a secondary tumor)]

A 59 years old woman who was admitted in our hospital had developed two primary melanomas at the lower leg during an interval of 15 years. The histologic diagnosis was a verrucous lentino maligna melanoma for both tumors. The differentiation from superficial spreading melanoma may be difficult. Interestingly enough, in our patient the formation of the new primary melanoma occurred simultaneously with the regression of the older one. In consequence, it seems that regression of a melanoma may not prevent from progression of the disease or from formation of a new primary melanoma.