Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

pH-sensitive hydrogels based on non-ionic acrylic copolymers

B Vázquez1, M Gurruchaga, I Goñi

  • 1Instituto de Ciencia y Tecnología de Polímeros, CSIC, Madrid, Spain.

Biomaterials
|April 1, 1997
PubMed
Summary

This study details the creation and swelling behavior of ethoxytriethyleneglycol monomethacrylate/methyl methacrylate hydrogels. Their hydration kinetics and diffusion coefficients were found to be pH-dependent and reversible, offering insights into smart material design.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incorporating Mn²⁺ ions in bioactive sol-gel coatings: Impact on cell adhesion, inflammation and bone regeneration.

Colloids and surfaces. B, Biointerfaces·2026
Same author

Few-cycle self-compression of GW mid-IR pulses in an anti-resonant fiber in ambient air: publisher's note.

Optics letters·2025
Same author

Few-cycle self-compression of GW mid-IR pulses in an anti-resonant fiber in ambient air.

Optics letters·2025
Same author

High-quality pulse compression using a hybrid all-bulk multipass cell scheme.

Optics express·2025
Same author

Quercetin-doped sol-gel coatings on titanium implants: a promising approach for enhanced immune response and cell adhesion.

Journal of materials chemistry. B·2025
Same author

Selective recovery of antimony from Sb-bearing copper concentrates by integration of alkaline sulphide leaching solutions and microwave-assisted heating: A new sustainable processing route.

The Science of the total environment·2024

Area of Science:

  • Polymer Chemistry
  • Materials Science
  • Biomaterials Engineering

Background:

  • Hydrogels are versatile polymeric networks capable of absorbing large amounts of water.
  • Understanding hydrogel swelling behavior is crucial for applications in drug delivery, tissue engineering, and sensors.
  • Ethoxytriethyleneglycol monomethacrylate and methyl methacrylate copolymers offer tunable properties for hydrogel development.

Purpose of the Study:

  • To synthesize and characterize hydrogels based on ethoxytriethyleneglycol monomethacrylate/methyl methacrylate copolymers.
  • To investigate the swelling behavior and hydration kinetics of these hydrogels in aqueous and buffered solutions.
  • To determine the influence of pH on hydrogel diffusion coefficients and assess the reversibility of the swelling process.

Main Methods:

Related Experiment Videos

  • Free radical polymerization was employed to synthesize the hydrogel copolymers at 70°C using 2,2'-azobisisobutyronitrile initiator.
  • Gravimetric analysis was used to measure water uptake over time during hydration in water and buffered solutions at various pH levels.
  • Swelling kinetics were analyzed using Fickian diffusion models, and diffusion coefficients were calculated.

Main Results:

  • The hydration kinetics followed Fickian diffusion laws for reduced sorption coefficients below 0.6.
  • Diffusion coefficients were observed to be lower at neutral pH compared to acidic or alkaline pH.
  • The diffusion coefficients appeared independent of the copolymer composition, and the swelling process demonstrated reversibility with pH changes.

Conclusions:

  • The synthesized hydrogels exhibit pH-dependent swelling behavior, with diffusion rates influenced by solution acidity/alkalinity.
  • The reversible nature of the swelling and desorption cycles indicates potential for stimuli-responsive applications.
  • The findings align with stress relaxation models, suggesting a rapid hydration process in these polymer networks.