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Prolonged succinylcholine-induced paralysis in connection with caesarean section. A case report
Acta Anaesthesiologica Scandinavica
|January 1, 1977
Summary
A healthy woman experienced prolonged paralysis after anesthesia due to low pseudocholinesterase levels. Genetic analysis revealed an atypical enzyme variant, impacting anesthetic drug metabolism.
Area of Science:
- Anesthesiology
- Clinical Biochemistry
- Human Genetics
Background:
- Succinylcholine is a common muscle relaxant used during anesthesia.
- Pseudocholinesterase (PChE) is an enzyme crucial for metabolizing succinylcholine.
- Atypical PChE variants can lead to prolonged paralysis after succinylcholine administration.