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Related Experiment Videos

Developmental dental changes in isolated cleft lip and palate

A N Pham1, W K Seow, S Shusterman

  • 1Children's Hospital, Harvard School of Dental Medicine, Boston, Massachusetts, USA.

Pediatric Dentistry
|March 1, 1997
PubMed
Summary

Children with cleft lip and/or palate (CL(P)) may experience delayed permanent tooth formation. This study found significantly lower dental maturity ratios in boys with CL(P) compared to controls.

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Area of Science:

  • Dentistry
  • Pediatric Dentistry
  • Craniofacial Anomalies

Background:

  • Cleft lip and/or palate (CL(P)) is a common congenital condition.
  • CL(P) can be associated with various developmental changes, including dental anomalies.

Purpose of the Study:

  • To investigate the hypothesis that permanent tooth formation is delayed in patients with CL(P).

Main Methods:

  • Dental maturity was assessed using the dental maturity ratio (DMR) from panoramic radiographs.
  • A cohort of patients with CL(P) was compared to a matched control group.
  • Statistical analysis was performed to compare DMR between groups.

Main Results:

  • Boys with CL(P) exhibited a significantly lower mean DMR compared to control boys (P < 0.05).

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  • A trend towards lower DMR was observed in cleft boys compared to cleft girls.
  • 67% of boys with CL(P) showed a delay in dental age, averaging 0.6 years.

    • Conclusions:

    • Cleft lip and/or palate may be associated with delayed permanent tooth formation, particularly in boys.
    • Further research may elucidate the mechanisms underlying dental development in CL(P) patients.