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Published on: February 21, 2018
Natural history of Menière's disease: staging the patients or their symptoms?
Abstract:
The issue of what can be considered "natural" in the evolution of Menière's disease is reassessed in terms of basic assumptions regarding the definition of this inner ear disorder. Strict principles for the identification of Menière's patients are recommended; i.e. episodic vertigo, fluctuating-ascending hearing loss and tinnitus, accompanied by a positive electrocochleographic pattern (summating/action potential ratio > 0.51). When considering the evolution of Menière's disease, it is worth stressing that almost all patients receive several different kinds of treatment which affect the natural course of the disease to different degrees. When staging the patients, a prodromic stage (Stage 0), with intermittent, isolated symptoms of variable duration, precedes the disabling stage (Stage I) with its full array of symptoms. Stage la can be distinguished from Stage Ib depending on the fluctuation in hearing and different therapeutic strategies can be proposed in order to reach the stabilised stage (Stage II). A limited number of patients are susceptible to either reverting into a disabling stage or progressing to Stage III, with possible involvement of the contralateral ear. We conclude that the full expression of the disease is a self-running course which can be only slightly modified by medical or surgical therapy but, instead, can be controlled by psychological counselling and dietary-hygienic principles.
Insights
Meniere's disease progression is reassessed, defining strict diagnostic criteria. While medical treatments offer slight modification, psychological and dietary approaches effectively control this inner ear disorder.
Area of Science:
- Otolaryngology
- Neurology
- Inner Ear Disorders
Background:
- Meniere's disease definition and natural evolution require reassessment.
- Current understanding of Meniere's disease progression is influenced by various treatments.
- Establishing clear diagnostic criteria is crucial for understanding disease evolution.
Purpose of the Study:
- To redefine the natural course of Meniere's disease.
- To propose strict diagnostic criteria for Meniere's disease.
- To evaluate the impact of treatments on Meniere's disease progression.
Main Methods:
- Reassessment of basic assumptions in Meniere's disease definition.
- Recommendation of strict diagnostic principles including electrocochleography.
- Staging of Meniere's disease based on symptom severity and hearing fluctuations.
Main Results:
- Proposed strict diagnostic criteria: episodic vertigo, fluctuating hearing loss, tinnitus, and positive electrocochleography (summating/action potential ratio > 0.51).
- Defined stages of Meniere's disease: prodromic (Stage 0), disabling (Stage I - Ia, Ib), stabilized (Stage II), and advanced (Stage III).
- Acknowledged that medical and surgical therapies have limited impact on the disease's natural course.
Conclusions:
- Meniere's disease is a self-limiting condition with a natural course that is minimally altered by medical or surgical interventions.
- Psychological counseling and dietary-hygienic principles are effective in managing Meniere's disease.
- Further research into the natural history and management of Meniere's disease is warranted.
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