Natural history of Menière's disease: staging the patients or their symptoms?

R Filipo1, M Barbara

  • 1Department of Otorhinolaryngology, University of Rome La Sapienza, Italy.

Insights

Meniere's disease progression is reassessed, defining strict diagnostic criteria. While medical treatments offer slight modification, psychological and dietary approaches effectively control this inner ear disorder.

Area of Science:

  • Otolaryngology
  • Neurology
  • Inner Ear Disorders

Background:

  • Meniere's disease definition and natural evolution require reassessment.
  • Current understanding of Meniere's disease progression is influenced by various treatments.
  • Establishing clear diagnostic criteria is crucial for understanding disease evolution.

Purpose of the Study:

  • To redefine the natural course of Meniere's disease.
  • To propose strict diagnostic criteria for Meniere's disease.
  • To evaluate the impact of treatments on Meniere's disease progression.

Main Methods:

  • Reassessment of basic assumptions in Meniere's disease definition.
  • Recommendation of strict diagnostic principles including electrocochleography.
  • Staging of Meniere's disease based on symptom severity and hearing fluctuations.

Main Results:

  • Proposed strict diagnostic criteria: episodic vertigo, fluctuating hearing loss, tinnitus, and positive electrocochleography (summating/action potential ratio > 0.51).
  • Defined stages of Meniere's disease: prodromic (Stage 0), disabling (Stage I - Ia, Ib), stabilized (Stage II), and advanced (Stage III).
  • Acknowledged that medical and surgical therapies have limited impact on the disease's natural course.

Conclusions:

  • Meniere's disease is a self-limiting condition with a natural course that is minimally altered by medical or surgical interventions.
  • Psychological counseling and dietary-hygienic principles are effective in managing Meniere's disease.
  • Further research into the natural history and management of Meniere's disease is warranted.

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