A comparison of three defined formula diets in normal volunteers

Defined formula diets, shown to be clinically effective in separate trials, have never been compared in the same subjects under identical controls. The intent of this study was to determine which one of three diets, (Vivonex, Flexical, or Precision LR) was most effectively absorbed and utilized. Stool weight and frequency, nitrogen balance and fecal fat, ash and moisture were measured. In addition, subjective comments were recorded regarding overall acceptability and ease of preparation. Statistically significant differences were found only in total stool weight. The data imply that the underlying disease state of the patient, the individual's response to the diet, the composition, cost, availability, and storage requirements of the diet must be taken into consideration when selecting a low residue formulation.